Joe Buettner: Oklahoma 38, Clemson 24
"OU and Clemson both have the offenses to post big numbers, but Deshaun Watson has shown to be more turnover prone than Baker Mayfield. If OU's defense can get after Watson early and force turnovers, the Sooners should be able to win with ease as long as the offense can string together consistent drives."
Spenser Davis: Oklahoma 34, Clemson 28
"Clemson is undoubtedly the best team the Sooners have faced in 2015, but Oklahoma has the talent — and depth — to deal with the Tigers. OU's depth at running back and defensive line will be the difference. "
Brady Vardeman: Oklahoma 54, Clemson 48
"This game features the country's two best quarterbacks in Deshaun Watson and Baker Mayfield. It's safe to say there will be points aplenty. The evening's first College Football Playoff will come down to the last touchdown scored. Confidence in my pick — zero.
